Tobacco use, symptom burden, and symptom management perspectives among adults with cancer: baseline results from 9 ECOG-ACRIN clinical trials

Authors: Price SN, Lee J-W, Gareen IF, Kircher SM, Kumar SK, Mayer IA, Saba NF, Fenske TS, Atkins MB, Hodi FS, Kyriakopoulos C, Tempany-Afdhal CM, Shanafelt TD, Park ER, Wagner LI

Category: Survivorship & Health Outcomes/Comparative Effectiveness Research
Conference Year: 2023

Abstract Body:
Purpose: Although extant research links tobacco use with worse treatment outcomes among adults with cancer, patient perceptions of the relationship between tobacco use and cancer-related symptoms are relatively unknown. Understanding the relationship between tobacco use and symptoms may help to inform tobacco treatment interventions tailored to the needs of individuals with cancer. Methods: This study includes enrollment data from 740 adults with breast, head and neck, leukemia, lymphoma, melanoma, myeloma, or prostate cancer enrolled in 9 ECOG-ACRIN Cancer Research Group trials (8 therapeutic, 1 imaging). Patient-reported outcomes included symptom severity and a modified Cancer Patient Tobacco Use Questionnaire. Patients who reported smoking within the last 30 days were considered currently smoking. The effects of smoking status (current, former, never) on the presence of each symptom (experienced at least "a little bit

Keywords: tobacco use; smoking; symptom management; pain; nausea