ASPO Abstracts
NATIONAL TRENDS OF METASTATIC BREAST CANCER AMONG WHITE AND BLACK PATIENTS.
Category: Cancer Health Disparities
Conference Year: 2022
Abstract Body:
Purpose: Breast cancer is the most common malignancy in women living in the United States (US). Studies have shown an association between sociodemographic factors and mortality from breast cancer in the US population. Our study aimed to understand the impact of sociodemographic factors on the prevalence of Metastatic breast cancer (mBCa) among inpatient admissions in the US. Methods: Female patients aged ‚â• 18 years hospitalized with a primary or secondary diagnosis of mBCa between 2005 and 2014 were identified using the National Inpatient Sample (NIS) database. Patients were categorized as Non-Hispanic White (NHW) and Non-Hispanic Blacks (NHB). The primary outcome of interest was the trends in mBCa stratified by race, median household income, and geographic region. Secondary outcomes include trends in mortality. We used Statistical Package for the Social Sciences (SPSS) software version 27 for analysis.Results: A total of 110,749 female patients with mBCa were identified in the study population. NHW were 80.2% and NHB were 19.8%. Among NHB, patients in the lowest income quartile (LIQ) had over three times the proportion of mBCa compared to those in the highest income quartile (HIQ) (47.8% vs. 13.8%; p <0.001). Alternatively, NHW patients in the HIQ had the highest proportion of mBCa compared to those in the LIQ (29.6% vs. 20%; p<0.001). While the trend in the prevalence of mBCa declined over the years in NHW (2005 vs. 2014; 75% vs. 66%; p<0.001), the NHB population had an upward trend (2005 vs. 2014; 13.1% vs. 18.8%; p<0.001). Among patients in the LIQ, NHB had two times the prevalence of mBCa admissions than NHW (47.8% vs. 20%).By geographical regions, the Southeast had the highest proportion of mBCa compared to other regions in both NHW and NHB (36.8% vs. 51.5%; p<0.001). We also observed a significant decline in inpatient mortality in NHB (2005 vs. 2014; 11.5% vs 8.7%; p=0.006).Conclusion: Sociodemographic factors, including income and geographic region, are potential contributors to the differences observed in mBCa admissions among NHW and NHB. Further studies exploring the relationships between mBCa and these sociodemographic factors will aid in new strategies to reduce breast cancer disparities amongst women living in the US.
Keywords: Health disparities, Metastatic Breast Cancer, Trend.