ASPO Abstracts
Determinants of willingness to conduct self-collection for cervical cancer screening among a national sample of women aged 30-45 years in the United States
Category: Early Detection & Risk Prediction
Conference Year: 2022
Abstract Body:
Background: Self-collection of vaginal samples for human papillomavirus (HPV) testing is a novel method to increase cervical cancer screening coverage by addressing obstacles to traditional screening, such as access. Our objective was to evaluate determinants of willingness to perform self-collection among a national sample of women in the United States. Methods: A quantitative survey of 4,000 Ipsos KnowledgePanel panelists (directly or through partners) aged 18-45 years to evaluate HPV-associated cancer prevention. Here, we focus on women between the ages of 30-45 years based on HPV testing eligibility per USPSTF guidelines to determine willingness to complete an HPV self-sample at home or at the healthcare office. We evaluated several determinants including sociodemographics, cervical cancer screening history, cancer risk perception, HPV knowledge, and attitudes towards medical care. We conducted descriptive comparisons of determinants by willingness to use self-collection methods using Chi-square and Wilcoxon tests. Results: Our study included 730 women (Avg age: 36 years); 81% non-Hispanic White, 52% with a Bachelor's degree or above, and 44% with an annual income ‚â•$75,000. One-third reported a history of HPV testing with 28% reporting they were diagnosed with HPV. Overall, about 80% percent reported they would be willing to use an HPV self-collection test. Women with only a high school degree (p=.010), and low annual income of $19,999 or less (p=0.001) were least likely to be willing to self-collect. Women who ever had an HPV test were more willing to use self-collection compared to those who had not (85%,75% p=0.007). Women who knew someone diagnosed with HPV were more likely to be willing to self-collect (87%vs. 77%, p=0.001) as were women who ever had an abnormal Pap (83% vs.79%, p=0.032). Women who were willing to self-collect were more likely to have more knowledge about HPV (Med. score:10 vs.8, p<0.001), and higher perceived risk (Med. Score:3 vs.2.5, p<0.001). Conclusion: Low socioeconomic status and perceived risk of HPV may influence willingness to use self-collection for screening. Next steps include multivariable analyses of determinants of willingness to conduct self-collection for HPV testing to inform pilot intervention project development.
Keywords: Cervical cancer screening, HPV testing, self-collection, home-based testing