Clinical and demographic factors associated with follow-up in a hospital-based exercise oncology program

Authors: Dunston ER, Walker D, White S, Ulrich CM, Oza S, Zingg RW, Hansen PA, Coletta AM

Category: Survivorship & Health Outcomes/Comparative Effectiveness Research
Conference Year: 2021

Abstract Body:
PURPOSE: To identify factors associated with returning for a follow-up assessment after participation in Huntsman Cancer Institute's Exercise Oncology Program, (Personal Optimism With Exercise Recovery, POWER). METHODS: Data were extracted from the electronic medical record and exercise oncology program databases for patients who participated in POWER, between 2016-2019. Clinical factors included body mass index (BMI), waist circumference, cancer type, cancer stage, and recent cancer treatment history (surgery, radiation, immunotherapy, chemotherapy, hormone therapy, bimodal, and multimodal therapy). Recent treatment history was defined as occurrence within 12- months of enrollment in POWER. Demographic factors included age, sex, ethnicity, race, and residence in an urban or rural area. Binary logistic regressions were utilized to identify clinical and demographic factors associated with not returning for follow-up. The cancer treatment and cancer stage models were adjusted for BMI, age, sex, and urban/rural status. The cancer type model was also adjusted for BMI, age, sex, urban/rural status, and number of recent cancer treatments. RESULTS: Among 849 cancer patients (61.3±13.6 years; 62% females; 91% white; 95% non- Hispanic) nearly 30% returned for a follow-up assessment, and the most prevalent cancer types in this cohort were breast (34%), prostate (13%), and multiple myeloma (8%). The following clinical and demographic factors were significantly associated with not returning for follow-up: male sex (OR 1.70, 95% CI 1.23,2.35), overweight BMI (25.00-29.99 kg/m^2; OR 1.62, 95% CI 1.11, 2.38), and greater waist circumference (OR 1.01, 95% CI 1.00,1.02). In the model further adjusted for cancer type, only multiple myeloma (OR 2.25; 95% CI 1.03,4.89) and endometrial cancer (OR 0.40, 95% CI 0.17,0.95) were associated with not returning for follow-up assessments. No other factors (unadjusted or adjusted) were significantly associated with not returning for follow-up. CONCLUSIONS: Male sex, overweight BMI, waist circumference, and cancer type may indicate survivors who are less likely to return for follow-up assessments in a hospital-based exercise oncology program. Findings may facilitate interventions to encourage follow-up and promote exercise engagement.

Keywords: exercise oncology survivorship