ASPO Abstracts
Feasibility of Beans/Bran Enriching Nutritional Eating For Intestinal health & Cancer Including Activity for Longevity (BENEFICIAL), a pilot trial to improve healthy lifestyles among individuals at high risk for colorectal cancer
Category: Lifestyles Behavior, Energy Balance & Chemoprevention
Conference Year: 2020
Abstract Body:
Purpose: To evaluate the feasibility of an intervention to increase dietary fiber from rice bran (RB) and navy beans
(NB) among individuals at high risk for colorectal cancer, while measuring physical activity (PA).
Methods: A 12-week, pilot, randomized, single-blind, dietary intervention comparing RB+NB to a fibersol-2 a
placebo control. Participants were ≥18 years of age, had one or more adenomatous polyps removed ≤3 years, and
had not received chemotherapy or radiotherapy with their surgical removal of polyps/tumors. Three-day food logs
were analyzed using Nutritionist Proâ„¢ to estimate caloric and fiber intake, macronutrient and micronutrient
consumption. The Automated Self-Administered 24-hour (ASA24®) Dietary Assessment Tool, and a SAS macro
was used to calculate Healthy Eating Index (HEI). PA was measured at baseline and post-intervention using an
activPAL accelerometer. Feasibility was assessed by recruitment and retention rates, compliance to RB+NB
intervention and PA measurement procedures, and median percent change from baseline to post-intervention for
fiber, HEI whole grain and HEI total scores.
Results: Out of N=68 assessed for eligibility, N=23 enrolled (33.8% accrual), and N=20 completed the intervention
(86.9% retention). Compliance was 92% in the RB+NB intervention vs. 89% in the fibersol-2 control. In the RB+NB
group, consumption of NB increased from 2 g/day to 30 g/day, and RB from 0 g/day to 30 g/day. Compliance with
activPAL procedures and provision of valid data (≥10 hours of wear time per day, for ≥4 days) was 100%. Fiber
intake (g/day) increased by 73% in RB+NB, and 82% in fibersol-2. HEI whole grain score improved by 270% in
RB+NB, and 37% in fibersol-2. HEI total score improved by 10% in RB+NB, and 9.1% in fibersol-2.
Conclusions: This pilot study supports the feasibility of a RB+NB intervention that included PA measurement.
Participants were compliant to the RB+NB intervention and showed greater increases in whole grain intake than
the Fibersol control. A larger trial is warranted to evaluate efficacy of RB+NB consumption, and PA changes on
metabolic and cancer-related outcomes.
Keywords: colon cancer, prevention, fiber