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In clinical trials, participants experienced an impressive average reduction in mass of 15% to 17% over 68 weeks
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"Once you start messing with all those signals — and it may be different from day to day, or when you took the drug — you really have a lot of potential for dysgeusia, or taste distortions." Semaglutide also tends to make people nauseous, and too much nicotine can have the same effect, said University of Pennsylvania psychiatry professor Matt Hayes
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