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Mojsov received the prize for her discovery of glucagon-like peptide 1 (GLP-1), an incretin hormone produced by gut tissue that plays a key role in insulin secretion and glucose metabolism
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Cardiovascular Outcomes# EXSCEL Trial (Exenatide)# The EXSCEL trial (Holman et al., NEJM 2017) enrolled 14,752 patients with T2D (73.1% with prior CV disease): Primary MACE: HR 0.91 (95% CI 0.83-1.00, p=0.06 for superiority) Non-inferiority achieved
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