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Patients should contact their GP or diabetes specialist if they experience: Persistent vomiting preventing adequate fluid intake Severe abdominal pain Signs of dehydration Inability to tolerate any oral intake Symptoms not improving after 2–3 weeks at a stable dose In cases of intolerable symptoms despite optimisation , temporary dose reduction, switching to an alternative GLP-1 agent, or considering other therapeutic options may be appropriate

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[22] [23] Acute cannabis use can cause fluctuations in blood sugar levels, though the direction and magnitude of these changes can vary considerably between individuals