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The in vitro study showed that PEG2k-N-GLP-1 exhibited a significant reduction in potency, which is likely due to the steric hindrance of PEG shielding the GLP-1 receptor interaction [102]

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doi: 10.3389/fendo.2022.1004044 Received 26 July 2022 Accepted 27 September 2022 Published 13 October 2022 Volume 13 - 2022 Edited by Åke Sjöholm, Gävle Hospital, Sweden Reviewed by Finbarr P