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The effect of glucagon-like peptide-1 (GLP-1) receptor agonists on substance use disorder (SUD)-related behavioural effects of drugs and alcohol: A systematic review

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This is why fatigue on GLP-1 treatment is often worse than it needs to be - it's not purely a medication side effect, it's partly a sign that the body needs more consistent nutritional support than a suppressed appetite is prompting you to give it