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Additionally, GLP-1 receptor activation in the nucleus tractus solitarius and area postrema of the brainstem, regions involved in visceral sensory processing and emetic reflexes, accounts for both the appetite-suppressing effects and the nausea that represents the most common adverse effect of the drug class

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A 2015 study — funded by Novo Nordisk — included more than 3,700 participants who didn't have type 2 diabetes