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Moreover, GLP-1RAs can reverse EndMT induced by high glucose and IL-1β via activating the AMPK pathway, which was evidenced by augmenting an endothelium marker expression (CD31), as well as alleviating mesenchymal markers expression (SM22α (sensitive 22 kDa actin-binding protein of the calponin), vimentin and Snail) [119]
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[27] It can be administered by subcutaneous injection or taken orally
