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This list is current as of April 2025, and may be updated over time as new indications are approved and/or new guidelines published or updated

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If digoxin levels are too low , you might notice signs like: Worsening shortness of breath Unusual fatigue Irregular or rapid heartbeat New swelling in your ankles or legs If digoxin levels are too high (toxicity) , symptoms could include: Nausea or vomiting Loss of appetite Confusion Visual changes, like halos around lights Abnormal heart rhythms Management Strategies To stay safe, your healthcare provider will likely monitor your digoxin levels more closely when starting or stopping GLP-1 therapy