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Tirzepatide has shown an ability to mobilize “stubborn fat” stores, likely through: Enhanced lipolysis Regulation of adipokines Mitochondrial activation and metabolic reprogramming of fat tissue Furthermore, the drug’s proven benefits in conditions like heart failure with preserved ejection fraction (HFpEF) and metabolic-associated steatohepatitis (MASH)-both of which involve fat accumulation and fibrosis-bolster its case as a lipedema treatment

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Your body is essentially trying to conserve energy