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--- This year brought 26 biosimilars that were approved by the FDA A significant portion of them (16) were denosumab biosimilars: ↳ 8 biosimilars referencing Prolia (denosumab for osteoporosis) ↳ Additional 8 biosimilars referencing Xgeva (denosumab for cancer-related bone disease) The downstream effects compound: ↳ Biosimilars typically reduce costs by 15-35% compared to reference products (this can decrease more as additional biosimilar options become available) ↳ Price competition benefits the entire therapeutic category ↳ Patients who couldn't afford brand therapy now have accessible options ↳ Health systems gain formulary flexibility without compromising clinical outcomes --- The 26 biosimilar approvals in 2025 represent thousands of patients gaining affordable access to proven therapies that may have previously been out of reach
