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Research shows that GLP-1 receptor agonists like semaglutide typically do not directly interact with common antihypertensive drugs, but weight loss itself can lower blood pressure readings, sometimes requiring medication adjustments
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In a slightly different but related way, GLP-1 receptors that are activated in the mesolimbic reward pathway diminish the reward sensation associated with food – this decreases the motivation to consume foods that are highly calorific and palatable
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