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These include nausea, vomiting, diarrhoea, abdominal pain, and constipation, which typically occur during dose initiation or escalation and often diminish over time as the body adjusts to the medication
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Cardiovascular Outcomes# EXSCEL Trial (Exenatide)# The EXSCEL trial (Holman et al., NEJM 2017) enrolled 14,752 patients with T2D (73.1% with prior CV disease): Primary MACE: HR 0.91 (95% CI 0.83-1.00, p=0.06 for superiority) Non-inferiority achieved
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