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[24] [1] Alcohol consumption can exacerbate these gastrointestinal side effects, potentially leading to increased discomfort, dehydration, and poor medication tolerance

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individuals with pre-existing retinopathy should be aware of this risk [28] [29] Pregnancy and breastfeeding — incretin-based therapies should be avoided during pregnancy and breastfeeding unless within a supervised clinical trial, as safety data in these populations are absent Delayed gastric emptying — a class effect of GLP-1 receptor agonists — can reduce the absorption rate of concomitant oral medicines