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Specifically, the ELIXA (lixisenatide) trial studied patients with T2DM who had recent acute coronary syndrome and found that the addition of lixisenatide to conventional therapy did not result in a significant difference in cardiovascular endpoints relative to placebo (Table 1) [56]
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It had also been discounted for the treatment of obesity because there was some prec-clinical evidence to suggest it was linked with weight gain
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