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In adults with relatively intact basal glucose regulation, it is less likely to cause excessive lowering of blood glucose levels (Eli Lilly and Company, 2026)
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Dosing follows evidence-based titration schedules, typically starting semaglutide at 0.25 mg weekly with gradual increases to therapeutic levels between 1.0-2.4 mg weekly, or tirzepatide beginning at 2.5 mg weekly with potential escalation to 15 mg weekly based on individual response and tolerance
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