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Although early studies were unclear (92), more recent studies with Western blotting, immunolocalization, and PCR have shown the presence of GLP-1R in acinar and in some cases duct cells (54, 128)

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Consultant bariatric surgeon Ahmed Ahmed, from Imperial College Healthcare NHS Trust, said: “Unrealistic expectations of a weight-loss cure have been driven by social media, not science or medicine, and by marketing rather than public health