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As GLP-1 drugs go mainstream, this expert says health is more than a number on a scale

In a pooled analysis of clinical trials assessing patients with heart failure with preserved ejection fraction (HFpEF), including the STEP HFpEF and STEP HFpEF DM trials, as well as in the FLOW and SELECT trials, semaglutide improved New York Heart Association (NYHA) class II–IV symptoms, physical limitations, exercise function, associated with a 30% reduction of N-terminal pro-brain natriuretic peptide and a 31% reduction in the composite endpoint of cardiovascular death and the need for treatment intensification or hospitalization for heart failure-related events (HR 0.69

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Back Lunenfeld-Tanenbaum Research Institute (18 Dec 2023) 'From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1', News: Medical Life Sciences

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