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Interactions Some drugs can interact with topiramate, including: Antiepileptic drugs CNS depressants Oral contraceptives Lithium and other carbonic anhydrase inhibitors Hydrochlorothiazide Pioglitazone Amitriptyline Marijuana Avoid drinking alcohol and taking illegal drugs while taking topiramate

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Reduced Hyperactivity : Ritalin helps calm excessive activity by regulating overactive neural pathways