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Where the evidence stands an honest map Deeply characterized in rodent & primate models Large randomized Phase 3 trials in its class From the lab toward the clinic This compound's class has been through some of the largest randomized, placebo-controlled human trials in metabolic research — the SURMOUNT-class program

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These changes were accompanied by reductions in pro-inflammatory cytokines such as IL-6 and TNF-α and increases in the anti-inflammatory cytokine IL-10 [5]