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Their pleiotropic effects, which range from anti-inflammatory, antioxidant, and metabolic regulation to neuroprotective and endothelial-stabilizing properties, are mediated through complex intracellular pathways, including the PI3K/Akt, AMPK, and NF-κB signaling pathways
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When to stop using semaglutide for weight loss It may be necessary to stop using semaglutide medications, such as when adequate weight loss has been achieved or if the medication is causing severe side effects