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Despite advancements in pharmacotherapy, lifestyle interventions including dietary modifications, physical activity, and behavioral counseling remain the foundation of effective and sustainable obesity management, emphasizing the need for a holistic, patient-centered approach to long-term weight control

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Cells with less than 1000 genes or more than 20,000 genes, and cells with more than 10% (fetus) or 50% (pediatric and adult) of mitochondrial transcripts were considered as ambient RNA or doublet and excluded