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Somatostatin, secreted from pancreatic γ-cells, acts as an inhibitory paracrine to suppress glucagon release from pancreatic α-cells, and specific blockade of SSRT2 eliminates the inhibitory effect of GLP-1 on glucagon secretion
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GLP-1 medicines in neurodegenerative diseases Extensive preclinical evidence illustrates the anti-inflammatory and neuroprotective properties of GLP-1 medicines across multiple models of neurodegenerative disease, particularly Alzheimer’s disease (AD) and Parkinson’s disease (PD)
