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Discussion Our systematic review demonstrates that GLP-1 receptor agonists (GLP-1 RAs), including semaglutide, liraglutide, tirzepatide, and exenatide, offer sustained efficacy in weight management, with consistent improvements in glycemic control among patients with obesity or overweight

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It was found that GLP-1 affects the immune response and induces M2 macrophage polarization via STAT3 activation signalizing