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GLP-1 drugs like Ozempic may reduce Alzheimer's risk | Inc. Magazine posted on the topic | LinkedIn

Semaglutide, another modified analog of human GLP-1, is resistant to DPP-4 degradation, which enables a once-weekly injection (Lau et al., 2015)

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This is actually one argument in favor of microdosing , where gastrointestinal effects are minimized while anti-inflammatory receptor activation may still occur