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1-3 GIP receptors are found in the central nervous system (eg, pituitary gland, cerebral cortex, hippocampus, olfactory bulb), adrenal cortex, heart, adipose tissue, and bone

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Given that clinical trials often exclude those with mood disorders, heightened awareness and monitoring are crucial when prescribing GLP-1s to individuals with bipolar disorder, it is necessary to educate both medical professionals and patients regarding potential effects