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Some patients might experience changes in how their thyroid medication works if they experience weight loss from Semaglutide, as weight changes can affect thyroid hormone needs
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The within-individual variation from dose to dose in oral semaglutide bioavailability was relatively high, but as a result of daily dosing and a long plasma half-life (1 week), the variability of semaglutide exposure at steady state was considerably reduced
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