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Specifically, an RCT comparing the initial combination of a DPP-4 inhibitor with metformin versus sequential add-on therapy after metformin failure showed that the combination therapy delayed treatment failure without differences in safety or adverse effects [481]
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Lisinopril In patients with mild to moderate hypertension stabilized on lisinopril (5-20 mg/day), BYETTA (10 mcg twice daily) did not alter steady-state Cmax or AUC of lisinopril
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