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The REWIND trial enrolled 9,901 participants with type 2 diabetes and followed them for a median of 5.4 years
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Dosages as high as 9 mg and 10 mg of Mazdutide were trialed and generally well-tolerated with no serious adverse events, achieving a respective placebo-corrected body weight loss of − 9.8% and − 6.2% in overweight or obese Chinese adults [89]