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NICE guidance recommends GLP-1 receptor agonists as treatment options for type 2 diabetes in specific circumstances, typically when other medications have not achieved adequate glycaemic control or when weight loss would provide additional benefit
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The least-squares mean percentage change in body weight at 24 weeks in the retatrutide groups was −7.2% in the 1 mg group, and up to −17.5% in the 12 mg group, as compared with −1.6% in the placebo group
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